研究業績

1992 / 1993 / 1994 / 1995 / 1996 / 1997 / 1998 / 1999 / 2000 / 2001 / 2002 / 2003 / 2004 / 2005

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1992年

秋元健吾, 新免芳史, 天地輝夫, 清水昌, 山田秀明. ポリエン脂肪酸 (ジホモ－γ－リノレン酸・アラキドン酸). 機能性脂質の開発と応用 (佐藤清隆他監修). p.130-141, シーエムシー, 東京 (1992).

Amano, N., Y. Shinmen, K. Akimoto, H. Kawashima, T. Amachi, S. Shimizu a, H. Yamada. "Chemotaxonomic significance of fatty acid composition in the genus Mortierella (Zygomycetes, Mortierellaceae)." Mycotaxon, 4, 247-265 (1992).

Hirose, N., F. Doi, T. Ueki, K. Akimoto, S. Shimizu, H. Yamada. "Suppressive eefect of sesamin agaist 7,12-dimethylbenz[a]anthracene induced rat mammary carcinogenesis." Anticancer Res., 12(4), 1259-1266 (1992).

Jareonkitmongkol, S., H. Kawashima, S. Shimizu, H. Yamada. "Production of 5,8,11-cis-eicosatrienoic acid by a Δ12-desaturase-defective mutant of Mortierella alpina 1S-4." J. Am. Oil Chem. Soc., 69, 939-944 (1992).

Jareonkitmongkol, S., H. Kawashima, N. Shirasaka, S. Shimizu and H. Yamada. Production of Dihomo-γ-linolenic acid by a Δ5-desaturase-defective mutant of Mortierella alpina 1S-4. Appl. Environ. Microbiol., 58 (7), 2196-2200 (1992).

Jareonkitmongkol, S., S. Shimizu, H. Yamada. "Fatty acid desaturation-defective mutants of an arachidonic-acid-producing fungus, Mortierella alpina 1S-4." J. Gen. Microbiol., 138, 997-1002 (1992).

Kataoka, M., Y. Doi, T.-S. Sim, S. Shimizu, H. Yamada. "A novel NADPH-dependent carbonyl reductase of Candida macedoniensis: Purification and characterization." Arch. Biochem. Biophys., 294(2), 469-474 (1992).

Kataoka, M., Y. Nomura, S. Shimizu, H. Yamada. "Enzymes involved in the NADPH regeneration system coupled with asymmetric reduction of carbonyl compounds in microorganisms." Biosci. Biotechnol. Biochem., 56(5), 820-821 (1992).

Kataoka, M., H. Sakai, T. Morikawa, M. Katoh, T. Miyoshi,S. Shimizu, H. Yamada. "Characterization of aldehyde reductase of Sporobolomyces salmonicolor." Biochim. Biophys. Acta, 1122 (1), 57-62 (1992).

Kataoka, M., S. Shimizu, H. Yamada. "Purification and characterization of a novel FMN-dependent enzyme: Membrane-bound l-(⁺)-pantoyl lactone dehydrogenase from Nocardia asteroides." Eur. J. Biochem., 204(2), 799-806 (1992).

Kataoka, M., S. Shimizu, H. Yamada. "Distribution and immunochemical characterization of microbial aldehyde reductase." Arch. Microbiol., 157 (3), 279-283 (1992).

片岡道彦, 清水昌, 山田秀明. カルボニル還元酵素の機能と光学活性化合物生産への応用. 発酵工学, 70, 479-493 (1992).

木下英明, 池田篤治, 古賀晋治, 清水昌, 山田秀明. ヌクレオシドオキシダーゼ固定化ベンゾキノン含有グラファイトペースト電極の作製とその特性. 分析化学, 41, 179-183 (1992).

Kobayashi, M., H. Komeda, N. Yanaka, T. Nagasawa, H. Yamada. "Nitrilase from Rhodococcus rhodochrous J1: Sequencing and overexpression of the gene and identification of an essential cysteine residue." J. Biol. Chem., 267, 20746-20751 (1992).

Kobayashi, M., T. Nagasawa, H. Yamada." Enzymatic synthesis of acrylamide: A success story not yet over." Trends Biotechnol., 10(11), 402-408 (1992).

Kobayashi, M., N. Yanaka, T. Nagasawa, H. Yamada. "Primary structure of an aliphatic nitrile-degrading enzyme, aliphatic nitrilase, from Rhodococcus rhodochrous K22 and expression of its gene and identification of its active site residue." Biochemistry, 31(37), 9000-9007 (1992).

Shimizu, S., S. Jareonkitmongkol, H. Kawashima, K. Akimoto, H. Yamada. "Inhibitory effect of curcumin on fatty acid desaturation in Mortierella alpina 1S-4 and rat liver microsomes." Lipids, 27(7), 509-512 (1992).

Shimizu, S., M. Kataoka, K. Shimizu, M. Hirakata, K. Sakamoto, H. Yamada. "Purification and characterization of a novel lactonohydrolase, catalyzing the hydrolysis of aldonate lactones and aromatic lactones, from Fusarium oxysporum." Eur. J. Biochem., 209(1), 383-390 (1992).

Shimizu, S., H. Kawashima, K. Akimoto, Y. Shinmen, H. Sugano, H. Yamada. "Inhibition of Δ⁵-desaturase in polyunsaturated fatty acid biosynthesis by (-)-asarinin and (-)-epiasarinin." Phytochemistry, 31(3), 757-760 (1992).

Shimizu, S., H. Kawashima, M. Wada, H. Yamada. "Occurrence of a novel sterol, 24,25-methylenecholest-5-en-3β-ol, in Mortierella alpina 1S-4." Lipids, 27(6), 481-483 (1992).

Shimizu, S., J. Ogawa, M.C.-M. Chung, H. Yamada. "Purification and characterization of a novel enzyme, arylalkyl acylamidase, from Pseudomonas putida Sc2." Eur. J. Biochem., 209(1), 375-382 (1992).

Shimizu, S., J. Ogawa, H. Yamada. "Microbial asymmetric hydrolysis of N-acetyl-1-methyl-3-phenylpropylamine to optically active 1-methyl-3-phenylpropylamine." Appl. Microbiol. Biotechnol., 37(2), 164-168 (1992).

清水昌, 新免芳史, 秋元健吾, 菅野道廣, 山田秀明. 糸状菌による高度不飽和脂肪酸の生産. ビタミン, 66, 289-299 (1992).

Shimizu, S.,H. Yamada. Enzymatic synthesis of chiral intermediates for D-pantothenate synthesis. Opportunities of Industrial Enzymes (ed. by R. Heinemann and B. Wolnak). p.22-37, Bernard Wolnak and Associates, Chicago, Illinois (1992).

清水昌, 山田秀明. 有用油脂類の発酵生産－高度不飽和脂肪酸の生産を中心として－. 日本醸造協会誌, 87, 36-43 (1992).

清水昌, 山田秀明. カルボニル還元酵素の機能とその有用物質合成への応用. 微生物の機能開発－バイオ研究最前線－ (山田秀明他編). p.269-280. 学会出版センター. 東京 (1992).

清水昌, 山田秀明. 清酒酵母を用いるアデノシルメチオニンの生産. 清酒酵母の研究－80年代の研究－ (清酒酵母研究会編). p.163-168, 清酒酵母研究会, 東京 (1992).

Yamada, H., S. Shimizu. Microbial and Enzymatic Processes for the Production of Biologically and Chemically Useful Compounds. New Aspects of Organic Chemistry II. p.455-468, Kodansha, Tokyo (1992).

Yamada, H ,S. Shimizu. New functions of microbial enzymes and their industrial applications. Proceedings of BIO JAPAN'92 Symposium. p.317-325 (1992).

Yamada, H., S. Shimizu, Y. Shinmen, K. Akimoto. H. Kawashima. Production of polyunsaturated fatty acids by microorganisms. Proceedings of the first International Congress on "Vitamins and Biofactors in Life Science" (ed. by T. Kobayashi). p.225-258, Center for Academic Publications Japan, Tokyo (1992).

Yamada, H., S. Shimizu, Y. Shinmen, K. Akimoto, H. Kawashima, S. Jareonkitmongkol. Production of dihomo-γ-linolenic acid by a Δ5-desaturase-defective mutant of Mortierella alpina 1S-4. Industrial Application of Single Cell Oils (ed. by D.J. Kyle and C. Ratledge). p.118-138, American Oil Chemists' Society Champaign, Illinois (1992).

1992 / 1993 / 1994 / 1995 / 1996 / 1997 / 1998 / 1999 / 2000 / 2001 / 2002 / 2003 / 2004 / 2005

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